Week 10 NFL Betting Odds, ATS Trends, Rankings & Game Notes

There are plenty of NFL games to get excited for in Week 10, including seven division matchups and the latest chapter in the Ravens-Patriots rivalry. The Cowboys and Chiefs are among the teams on their bye week. Notably, there are more late-afternoon games (six) than early games (five) on Sunday, and FOX broadcasts outnumber CBS nine to three. Check out the entire rundown of games below plus betting odds, rankings, ATS trends, and notes.

Week 10 NFL Betting Lines & TV Info

rankings = scoring offense & defense

Indianapolis at Tennessee, 8:20pm (Thursday)

TV: FOX/NFLN
Line: Pick ‘Em
O/U: 48

Trends: Indianapolis (12-4-1 ATS in their last 17 Thursday games); Tennessee (4-13 ATS in last 17 games vs. IND)

Rankings: Indianapolis (Offense 15, Defense 3); Tennessee (Offense 7, Defense 16)

Notes: Tennessee hasn’t won at home vs. Indianapolis under Mike Vrabel (0-2).

Washington at Detroit, 1:00pm

TV: FOX
Line: DET -4.5
O/U: 47

Trends: Washington (1-4 ATS in last 5 games vs. DET); Detroit (1-4 ATS in last 5 home games); Totals (Under is 8-1-1 in last 10 meetings)

Rankings: Washington (Offense 30, Defense 11); Detroit (Offense 19, Defense 28)

Notes: Alex Smith will start for Washington, his first start since November 18, 2018.

Jacksonville at Green Bay, 1:00pm

TV: FOX
Line: GB -13.5
O/U: 50

Trends: Jacksonville (1-5 ATS in last 6 games); Green Bay (4-1 ATS in last 5 home games)

Rankings: Jacksonville (Offense 26, Defense 31); Green Bay (Offense 3, Defense 17)

Notes: Jacksonville hasn’t won since Week 1.

Tampa Bay at Carolina, 1:00pm

TV: FOX
Line: TB -5.5
O/U: 51

Trends: Tampa Bay (5-2 ATS in their last 7 games as a road favorite); Carolina (1-6-1 ATS in their last 8 home games)

Rankings: Tampa Bay Carolina Tampa Bay (Offense 9, Defense 9); Carolina (Offense 23, Defense 15)

Notes: Tom Brady has an 81.7 career passer rating vs. Carolina, his worst mark against any team he’s faced at least three times.

Philadelphia at NY Giants, 1:00pm

TV: FOX
Line: PHI -3
O/U: 44

Trends: Philadelphia (Offense 24, Defense 18); NY Giants (Offense 31, Defense 13)

Rankings: Philadelphia (1-5 ATS in their last 6 games as a favorite); NY Giants (3-10 ATS in their last 13 home games vs. NYG); Totals (Over is 10-1 in last 11 meetings at NYG)

Notes: The Giants are tied for the most ATS wins in the NFL this year (6). Philadelphia has the No. 4 in pass defense in football.

Houston at Cleveland, 1:00pm

TV: FOX
Line: CLE -3
O/U: 49

Trends: Houston (0-7 ATS in their last 7 games as an underdog); Cleveland (0-5 ATS in last 5 games vs. HOU); Totals (Under is 7-2 in their last 9 meetings)

Rankings: Houston (Offense 21, Defense 29); Cleveland (Offense 16, Defense 26)

Notes: Baker Mayfield has been activated from COVID-19 list.

Buffalo at Arizona, 4:05pm

TV: CBS
Line: ARI -2.5
O/U: 56

Trends: Buffalo (7-1-1 ATS in last 9 games in November); Arizona (1-5 ATS in last 6 games as home favorite.

Rankings: Buffalo (Offense 14, Defense 19); Arizona (Offense 6, Defense 8)

Notes:

LA Chargers at Miami, 4:05pm

TV: CBS
Line: MIA -2.5
O/U: 48

Trends: LA Chargers (1-4 ATS in last 5 road games vs. MIA); Miami (4-0 ATS in last 4 games)

Rankings: LA Chargers (Offense 17, Defense 21); Miami (Offense 10, Defense 4)

Notes: Matchup between two of the first three quarterbacks taken in the 2020 NFL Draft.

Denver at Las Vegas, 4:05pm

TV: CBS
Line: LV -4.5
O/U: 51

Trends: Denver (6-0 ATS in their last 6 games following an ATS loss); Las Vegas (4-0 ATS in last 4 games vs. AFC West)

Rankings: Denver (Offense 27, Defense 22); Las Vegas (Offense 11, Defense 24)

Notes:

San Francisco at New Orleans, 4:25pm

TV: FOX
Line: NO -9
O/U: 49

Trends: San Francisco (6-1 ATS in their last 7 games vs. NO); New Orleans (0-4 ATS in last 4 home games vs. SF); Totals (Over is 7-1-1 in last 9 meetings)

Rankings: San Francisco (Offense 25, Defense 10); New Orleans (Offense 4, Defense 14)

Notes:

Seattle at LA Rams, 4:25pm

TV: FOX
Line: LA -1.5
O/U: 55

Trends: Seattle (6-1-1 ATS in their last 8 games in November); LA Rams (6-2 ATS in last 8 home games vs. SEA)

Rankings: Seattle (Offense 1, Defense 30); LA Rams (Offense 22, Defense 2)

Notes:

Cincinnati at Pittsburgh, 4:25pm

TV: FOX
Line: PIT -7
O/U: 45

Trends: Cincinnati (6-1 ATS in their last 7 games overall); Pittsburgh (5-2 ATS in last 7 home games vs. CIN); Totals (Under is 4-0 in last 4 meetings)

Rankings: Cincinnati (Offense 20, Defense 20); Pittsburgh (Offense 5, Defense 5)

Notes: Bengals tied for most ATS wins in NFL (6).

Baltimore at New England, 8:20pm

TV: NBC
Line: BAL -7
O/U: 44

Trends: Baltimore (4-1-1 ATS in their last 6 road games vs. NE); New England (0-4-1 ATS in their last 5 games following an ATS win); Totals (Over is 4-0 in last 4 meetings)

Rankings: Baltimore (Offense 8, Defense 1); New England (Offense 28, Defense 12)

Notes: Cam Newton has a 106.7 career passer rating vs. Baltimore, his third-best mark. In two games, he didn’t throw an interception and was only sacked twice.

Minnesota at Chicago, 8:15pm

TV: ESPN
Line: MIN -2.5
O/U: 44

Trends: Minnesota (2-12 ATS in their last 14 Monday games); Chicago (5-1 ATS in last 6 games vs. MIN); Totals (Under is 5-1 in last 6 meetings in Chicago)

Rankings: Minnesota (Offense 12, Defense 25); Chicago (Offense 29, Defense 7)

Notes: Kirk Cousins is 0-9 in his career on Monday.